Research Scientist I

As a Research Scientist, you will leverage your deep scientific knowledge to support and facilitate the organization's research programs and projects. You are expected to apply various scientific principles to drive innovation.

Every day you will design and execute rigorous laboratory research, contributing to ongoing studies through meticulous analysis. You will also actively support manuscript preparation and participate in grant writing.

To be successful in this role, you will possess proven scientific expertise, a strong track record in experimental execution and analysis. Your ability to plan research, contribute to publications, and assist in securing funding will be paramount.

The Ivy Brain Tumor Center at Barrow Neurological Institute is a non-conventional non-profit program offering state-of-the-art clinical trials for patients with the most aggressive form of brain cancer. It is home to the largest collection of Phase 0 trials for brain tumors in the world. Our multidisciplinary team of brain tumor specialists and scientists are accelerating drug discovery and precision medicine in neuro-oncology to identify the most promising first-in-class therapies for brain tumor patients.

To facilitate the development of brain targeting therapeutics via neuro-pharmacokinetic characterization of various molecules through preclinical and clinical studies. Principal Duties and Responsibilities: We are looking for an individual to join the Pharmacokinetics (PK) Lab as a Research Scientist. The candidate should have a strong background in chemical/pharmaceutical sciences with a strong research experience in translational studies. Candidates should demonstrate significant experience in LC-MS/MS-based method development and validation in compliance with CAP/CLIA regulations and/or FDA guidelines and competency in pharmacokinetic data analysis. The candidate should be able to work well in highly collaborative environment and have excellent communication skills. Potential areas of application include bioanalysis method validation drug development drug pharmacokinetics biomarker analysis and PK modeling.

Key responsibilities include 

Development validation and implementation of analytical methods for various drugs drug candidates metabolites and biomarkers employing UHPLC and LC-MS/MS techniques.

Planning and conducting preclinical pharmacokinetic studies including drug formulations administration through various routes tissue perfusion harvesting and analysis.

Performing biochemical and physicochemical characterization of various molecules.

Performing pharmacokinetic data analyses and interpretation.

Oversight and implementation of multiple research projects.

Facilitates research activities in partnership with laboratory PI leveraging scientific experience.

Manuscript preparation and publishing.

Development of research projects assistance with grant proposals and applications.

Supervision and training of laboratory personnel including post-doctoral fellows PhD and undergrad students.

Preparation and delivery of research presentations at local meetings national and international conferences.

General operation maintenance and troubleshooting of lab equipment including UHPLC and LC-MS/MS.

Preparation and maintenance of required laboratory safety documentation and adherence to the guidelines and regulations in compliance with CAP/CLIA regulations and FDA guidelines.

Preferred Qualifications:

Postdoctoral training (5+ years) in bioanalysis pharmacology medicinal or pharmaceutical chemistry areas.

Proven record of UHPLC or LC-MS/MS-based assay development and validation in compliance with CAP/CLIA regulations and/or FDA guidelines.

Experience in pharmacokinetic study design execution data analyses and interpretation.

Experience in biomedical research (cellular techniques and preclinical efficacy studies).

Experience with maintenance and troubleshooting of LC and MS systems.

Excellent organizational and analytical skills.

Ability to work independently and cohesively as part of a team.

Additional Requirements Recommendation letters Education Ph.D. or equivalent degree (MD DVM PharmD etc.) in Pharmaceutical Sciences Chemistry Biochemistry Medical Sciences or in related disciplines.

Required

• Doctor of Medicine/Philosophy MD or Ph.D in Geography or Environmental Epidemiology 
• Five (5) years or equivalent of Geospatial and epidemiologic research- experience and data analysis/GIS analysis 
• Experience with a statistical package (R or Stata) and Geospatial Required and analysis
• Specialized computer analysis program experience (Use of High Performance Compute)

Hello Humankindness: Join a Legacy of Healing at Saint Joseph’s Hospital and Medical Center (SJHMC) 

Ready to make a real difference? Join SJHMC in Phoenix AZ., a 571-bed nonprofit founded by the Sisters of Mercy over 125 years ago. We're more than a hospital; we're a global destination for life-changing care, embracing patients with humankindness.

Here, your calling will flourish. We're not just a workplace; we're a community dedicated to a mission of service.

Leaders in Specialized Care:

• Barrow Neurological Institute (BNI): A world-renowned center for groundbreaking neurological research and innovative treatments.
• Norton Thoracic Institute (NTI): A national leader in advanced thoracic care with pioneering surgical techniques.
• Level I Trauma Center: One of Arizona's busiest ERs, providing immediate, comprehensive care for critically injured patients 24/7.

Why SJHMC?

• Culture of Excellence & Well-being: We care for our people, fostering professional and personal growth.
• Community & Collaboration: Be part of a network committed to global health and well-being.
• Join a Legacy, Shape a Future: Over 20% of our patients travel internationally for our specialized care.

This is an invitation to join a family of dedicated professionals at the forefront of medical innovation, united by the power of humankindness.